Just think of it as the Yellowstone effect. On Tuesday, ABC announced that Grey’s Anatomy is getting another spinoff — and this one’s set in Texas.
Seemingly responding to the ever-expanding Yellowstone western franchise on Paramount+, this Grey’s offshoot will follow doctors at a rural West Texas medical centre. Deadline broke the news, describing the untitled show as an “edgy” drama.
The creative team behind it seems stacked for success.
Shonda Rhimes, who created Grey’s Anatomy, is also a mastermind for this series. She’ll write and executive-produce it with Grey’s showrunner and executive producer Meg Marinis.
Ellen Pompeo, the original star of Grey’s and a current executive producer, is on board to executive-produce the new show as well.
“I am incredibly excited to expand the Grey’s Anatomy universe,” Marinis told Deadline. “This opportunity will bring new characters and stories to life that will embody the same heart, emotion and connection audiences have loved from Grey’s for more than two decades — all set in my home state of Texas.
“I am so grateful to Shonda Rhimes for creating this dynamic world and feel so fortunate that I get to be a part of it.”
Execs at ABC gave the new show a straight-to-series order. It’ll premiere in midseason 2027.

Grey’s Anatomy, which is now in its 22nd season, has already launched two other spinoffs. Private Practice starred Kate Walsh and debuted in 2007, lasting six seasons. Station 19 starred Jason George’s and hit screens in 2018, wrapping up after seven seasons.
As Deadline notes, the Texas-set offshoot is the first in the Grey’s universe to be set outside of a big city. (Both the original show and Station 19 called Seattle home, while Private Practice set up shop in Los Angeles.) It’s also the first spinoff to not centre on a series regular character from the main show.
“While the spinoff will be built around a new group of doctors, it will likely be connected to the world of Grey’s Anatomy via one or more characters, possibly Debbie Allen’s Catherine Fox, I hear,” wrote Deadline reporter Nellie Andreeva.
Grey’s Anatomy first scrubbed in on ABC in 2005, and in 2019 it surpassed ER to become the longest-running prime-time medical drama in the U.S. The series aired its 450th episode in October 2025.
“Obviously I never anticipated the show still being the No. 1 show on the network,” Pompeo previously told People.
“How do you walk away from a hit? The fans will dictate when the show ends. As much as we think we’re in control, we’re not. It’s the fans’ show at this point. They control how long the show goes. We’ll see. I kind of just take it year by year and see.”